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验证数据展示

  • WB analysis of mouse brain using 67640-1-Ig (same clone as 67640-1-PBS)

    WB analysis of mouse brain using 67640-1-Ig (same clone as 67640-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 67640-1-Ig (PHLPP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67640-1-PBS in a different storage buffer formulation.

PHLPP Monoclonal antibody, PBS Only

PHLPP Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67640-1-PBS

产品说明书

CloneNo. 2E8E6

宿主/亚型

Mouse / IgG2b

种属反应性

Human, mouse , rat, pig

应用

WB, Indirect ELISA

别名

hSCOP, KIAA0606, PHLPP, PHLPP1, PLEKHE1, SCOP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

67640-1-PBS targets PHLPP in WB, Indirect ELISA applications and shows reactivity with Human, mouse , rat, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse , rat, pig
免疫原 PHLPP fusion protein Ag18982 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 PH domain and leucine rich repeat protein phosphatase
别名 hSCOP, KIAA0606, PHLPP, PHLPP1, PLEKHE1, SCOP
计算分子量 1717 aa, 184 kDa
观测分子量 185 kDa
GenBank蛋白编号BC126277
基因名称 PHLPP
Gene ID (NCBI) 23239
RRIDAB_2882840
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO60346
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PHLPP (PH domain leucine-rich-repeats protein phosphatase) belongs to a novel family of Ser/Thr protein phosphatases that consists of PHLPP1 and PHLPP2 isoforms. It has been shown that PHLPP negatively regulates multiple oncogenic pathways by directly dephosphorylating and inactivating key signaling molecules, including Akt, S6K, and RAF1. Observed MW of PHLPP is 185 kDa.