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PHLPP Monoclonal antibody, PBS Only

PHLPP Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

Human, mouse , rat, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2E8E6

Cat no : 67640-1-PBS

Print datasheet

Synonyms

hSCOP, KIAA0606, PHLPP, PHLPP1, PLEKHE1, SCOP

验证数据展示

  • WB analysis of mouse brain using 67640-1-Ig (same clone as 67640-1-PBS)

    WB analysis of mouse brain using 67640-1-Ig (same clone as 67640-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 67640-1-Ig (PHLPP antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67640-1-PBS in a different storage buffer formulation.

产品信息

67640-1-PBS targets PHLPP in WB, Indirect ELISA applications and shows reactivity with Human, mouse , rat, pig samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse , rat, pig
Immunogen PHLPP fusion protein Ag18982 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name PH domain and leucine rich repeat protein phosphatase
Synonyms hSCOP, KIAA0606, PHLPP, PHLPP1, PLEKHE1, SCOP
Calculated Molecular Weight 1717 aa, 184 kDa
Observed Molecular Weight 185 kDa
GenBank Accession NumberBC126277
Gene Symbol PHLPP
Gene ID (NCBI) 23239
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO60346
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PHLPP (PH domain leucine-rich-repeats protein phosphatase) belongs to a novel family of Ser/Thr protein phosphatases that consists of PHLPP1 and PHLPP2 isoforms. It has been shown that PHLPP negatively regulates multiple oncogenic pathways by directly dephosphorylating and inactivating key signaling molecules, including Akt, S6K, and RAF1. Observed MW of PHLPP is 185 kDa.