验证数据展示
产品信息
27921-1-PBS targets PI3 Kinase p110 Alpha in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | PI3 Kinase p110 Alpha fusion protein Ag27539 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | phosphoinositide-3-kinase, catalytic, alpha polypeptide |
Synonyms | |
Calculated Molecular Weight | 1068 aa, 124 kDa |
Observed Molecular Weight | 110 kDa |
GenBank Accession Number | BC113601 |
Gene Symbol | PIK3CA |
Gene ID (NCBI) | 5290 |
RRID | AB_2918135 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P42336 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).