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PI3 Kinase p110 Beta Monoclonal antibody, PBS Only

PI3 Kinase p110 Beta Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1B2A1

Cat no : 67121-1-PBS

Print datasheet

Synonyms

PI3K p110(beta), PIK3CB, PI3K, PI3 kinase subunit beta, p110 BETA

验证数据展示

  • WB analysis using 67121-1-Ig (same clone as 67121-1-PBS)

    WB analysis using 67121-1-Ig (same clone as 67121-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67121-1-Ig (PIK3CB antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67121-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 67121-1-Ig (same clone as 67121-1-PBS)

    IHC staining of human lung cancer using 67121-1-Ig (same clone as 67121-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67121-1-Ig (PIK3CB antibody) at dilution of 1:300 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67121-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 67121-1-Ig (same clone as 67121-1-PBS)

    IHC staining of human lung cancer using 67121-1-Ig (same clone as 67121-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 67121-1-Ig (PIK3CB antibody) at dilution of 1:300 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67121-1-PBS in a different storage buffer formulation.

产品信息

67121-1-PBS targets PI3 Kinase p110 Beta in WB, IHC, Indirect ELISA applications and shows reactivity with human, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, rat
Immunogen PI3 Kinase p110 Beta fusion protein Ag17505 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name phosphoinositide-3-kinase, catalytic, beta polypeptide
Synonyms PI3K p110(beta), PIK3CB, PI3K, PI3 kinase subunit beta, p110 BETA
Calculated Molecular Weight 1070 aa, 123 kDa
Observed Molecular Weight 120-130 kDa
GenBank Accession NumberBC114432
Gene Symbol PI3 Kinase p110 Beta
Gene ID (NCBI) 5291
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP42338
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PIK3CB(phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform) is also named as PIK3C1, PI3K-beta, p110beta. The gene encodes a 1070 amino acid protein which belongs to the PI3/PI4-kinase family. Phosphoinositide 3-kinases (PI3Ks) have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. The class I PI3 kinases are heterodimers composed of 110 kDa catalytic subunits that associate with regulatory adaptor proteins. Four class I catalytic subunits have been identified, PIK3CA (p110α), PIK3CB (p110β), PIK3CD (p110δ) and PIK3CG (p110γ)(PMID:19177002).