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  • Featured Product
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PITX2 Monoclonal antibody, PBS Only

PITX2 Monoclonal Antibody for Indirect ELISA, WB

Host / Isotype

Mouse / IgG1

Reactivity

rat, mouse, human

Applications

Indirect ELISA, WB

Conjugate

Unconjugated

CloneNo.

1E3B1

Cat no : 67201-1-PBS

Print datasheet

Synonyms

RIEG bicoid-related homeobox transcription factor, Paired-like homeodomain transcription factor 2, ARP1, ALL1-responsive protein ARP1, 1E3B1

验证数据展示

  • WB analysis using 67201-1-Ig (same clone as 67201-1-PBS)

    WB analysis using 67201-1-Ig (same clone as 67201-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67201-1-Ig (PITX2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Beta Actin Monoclonal antibody (HRP-66009) as loading control. This data was developed using the same antibody clone with 67201-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 67201-1-Ig (same clone as 67201-1-PBS)

    WB analysis of HEK-293 using 67201-1-Ig (same clone as 67201-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 67201-1-Ig (PITX2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67201-1-PBS in a different storage buffer formulation.

产品信息

67201-1-PBS targets PITX2 in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.

Tested Applications Indirect ELISA, WB Application Description
Tested Reactivity rat, mouse, human
Immunogen PITX2 fusion protein Ag27924 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name paired-like homeodomain 2
Synonyms RIEG bicoid-related homeobox transcription factor, Paired-like homeodomain transcription factor 2, ARP1, ALL1-responsive protein ARP1, 1E3B1
Calculated Molecular Weight 36 kDa
Observed Molecular Weight 30 kDa
GenBank Accession NumberBC013998
Gene Symbol PITX2
Gene ID (NCBI) 5308
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ99697
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PITX2 belongs to the bicoid class of homeodomain transcription factors, which play essential roles in embryonic development. Various PITX2 isoforms are involved in a wide variety of developmental programs, including left-right signaling. It controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, PITX2 is involved in the expansion of muscle progenitors. In addition, it may play a role in the proper localization of asymmetric organs such as the heart and stomach. PITX2 can be bound by some other proteins, and are part of a much larger atrial transcriptional complex. This antibody specifically recognizes isoform PTX2C.