验证数据展示
产品信息
67201-1-PBS targets PITX2 in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.
经测试应用 | Indirect ELISA, WB Application Description |
经测试反应性 | rat, mouse, human |
免疫原 | PITX2 fusion protein Ag27924 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | paired-like homeodomain 2 |
别名 | RIEG bicoid-related homeobox transcription factor, Paired-like homeodomain transcription factor 2, ARP1, ALL1-responsive protein ARP1, 1E3B1 |
计算分子量 | 36 kDa |
观测分子量 | 30 kDa |
GenBank蛋白编号 | BC013998 |
基因名称 | PITX2 |
Gene ID (NCBI) | 5308 |
RRID | AB_2882494 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q99697 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PITX2 belongs to the bicoid class of homeodomain transcription factors, which play essential roles in embryonic development. Various PITX2 isoforms are involved in a wide variety of developmental programs, including left-right signaling. It controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, PITX2 is involved in the expansion of muscle progenitors. In addition, it may play a role in the proper localization of asymmetric organs such as the heart and stomach. PITX2 can be bound by some other proteins, and are part of a much larger atrial transcriptional complex. This antibody specifically recognizes isoform PTX2C.