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验证数据展示

  • IHC staining of human stomach cancer using 11942-1-AP

    IHC staining of human stomach cancer using 11942-1-AP

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 11942-1-AP (PKIB antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human stomach cancer using 11942-1-AP

    IHC staining of human stomach cancer using 11942-1-AP

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 11942-1-AP (PKIB antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

PKIB Polyclonal antibody

PKIB Polyclonal Antibody for IHC, ELISA
Cat No. 11942-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, ELISA

别名

PKI beta, PKIB, PRKACN2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inhuman stomach cancer tissue, human gliomas tissue, mouse kidney tissue, mouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11942-1-AP targets PKIB in IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 PKIB fusion protein Ag2541 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 protein kinase (cAMP-dependent, catalytic) inhibitor beta
别名 PKI beta, PKIB, PRKACN2
计算分子量 78 aa, 9 kDa
GenBank蛋白编号BC036011
基因名称 PKIB
Gene ID (NCBI) 5570
RRIDAB_3085384
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9C010
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The cAMP-dependent protein kinase inhibitor-β (PKIB) is also named as PRKACN2. PKIB is presumed to be one of the regulatory factors controlling the cAMP-dependent protein kinase A signaling pathway (PMID: 23224602). PKIB plays an important role in regulating the proliferation, migration, and even metastasis of osteosarcoma (PMID: 17195088). The expression of PKIB in the cytoplasm of tumor is closely related to pAkt and the triple negative breast cancer (PMID: 28387904).

实验方案

Product Specific Protocols
IHC protocol for PKIB antibody 11942-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols