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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 11540-1-AP (same clone as 11540-1-PBS)

    WB analysis using 11540-1-AP (same clone as 11540-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11540-1-AP (PLAGL2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11540-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

PLAGL2 Polyclonal antibody, PBS Only

PLAGL2 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 11540-1-PBS

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Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

11540-1-PBS targets PLAGL2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen PLAGL2 fusion protein Ag2137 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name pleiomorphic adenoma gene-like 2
Synonyms
Calculated Molecular Weight 496 aa, 55 kDa
Observed Molecular Weight 50-55 kDa, 70 kDa
GenBank Accession NumberBC023655
Gene Symbol PLAGL2
Gene ID (NCBI) 5326
RRIDAB_2165035
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UPG8
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PLAGL2, also named KIAA0198, belongs to the krueppel C2H2-type zinc-finger protein family. It shows weak transcriptional activatory activity. PLAGL2, a proto-oncogene, is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. PLAGL2 can function as a tumor suppressor by initiating cell cycle arrest and apoptosis. The calculated molecular weight of PLAGL2 is 55 kDa, but the SUMO1-modifIed form is 68 kDa (PMID: 30535429).