- Featured Product
- KD/KO Validated
PLAGL2 Polyclonal antibody, PBS Only
PLAGL2 Polyclonal Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
11540-1-PBS targets PLAGL2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | PLAGL2 fusion protein Ag2137 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | pleiomorphic adenoma gene-like 2 |
Synonyms | |
Calculated Molecular Weight | 496 aa, 55 kDa |
Observed Molecular Weight | 50-55 kDa, 70 kDa |
GenBank Accession Number | BC023655 |
Gene Symbol | PLAGL2 |
Gene ID (NCBI) | 5326 |
RRID | AB_2165035 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9UPG8 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PLAGL2, also named KIAA0198, belongs to the krueppel C2H2-type zinc-finger protein family. It shows weak transcriptional activatory activity. PLAGL2, a proto-oncogene, is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. PLAGL2 can function as a tumor suppressor by initiating cell cycle arrest and apoptosis. The calculated molecular weight of PLAGL2 is 55 kDa, but the SUMO1-modifIed form is 68 kDa (PMID: 30535429).