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PLCG2 Monoclonal antibody, PBS Only

PLCG2 Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

2F8H5

Cat No : 67011-1-PBS

Print datasheet

Synonyms

Phospholipase C gamma 2, Phospholipase C IV, PLC gamma 2, PLC IV, PLCG2, PLCγ2

验证数据展示

  • WB analysis of Ramos using 67011-1-Ig (same clone as 67011-1-PBS)

    WB analysis of Ramos using 67011-1-Ig (same clone as 67011-1-PBS)

    Ramos cells were subjected to SDS PAGE followed by western blot with 67011-1-Ig (PLCG2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67011-1-Ig (PLCG2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67011-1-Ig (PLCG2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

产品信息

67011-1-PBS targets PLCG2 in WB, IHC, ELISA applications and shows reactivity with Human samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity Human
Immunogen PLCG2 fusion protein Ag24355 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name phospholipase C, gamma 2 (phosphatidylinositol-specific)
Synonyms Phospholipase C gamma 2, Phospholipase C IV, PLC gamma 2, PLC IV, PLCG2, PLCγ2
Calculated Molecular Weight 148 kDa
Observed Molecular Weight 148 kDa
GenBank Accession NumberBC007565
Gene Symbol PLCG2
Gene ID (NCBI) 5336
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP16885
Storage Buffer PBS only
Storage ConditionsStore at -80°C.

背景介绍

Phospholipase C-gamma2 (PLCG2) is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor.IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.