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验证数据展示

  • WB analysis of Ramos using 67011-1-Ig (same clone as 67011-1-PBS)

    WB analysis of Ramos using 67011-1-Ig (same clone as 67011-1-PBS)

    Ramos cells were subjected to SDS PAGE followed by western blot with 67011-1-Ig (PLCG2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67011-1-Ig (PLCG2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PLCG2 antibody included
  • WB analysis of Karpas-422 using 67011-1-Ig (same clone as 67011-1-PBS)

    WB analysis of Karpas-422 using 67011-1-Ig (same clone as 67011-1-PBS)

    Karpas-422 cells were subjected to SDS PAGE followed by western blot with 67011-1-Ig (PLCG2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

  • WB analysis of rabbit spleen using 67011-1-Ig (same clone as 67011-1-PBS)

    WB analysis of rabbit spleen using 67011-1-Ig (same clone as 67011-1-PBS)

    Rabbit spleen tissue was subjected to SDS PAGE followed by western blot with 67011-1-Ig (PLCG2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    IHC staining of human tonsillitis using 67011-1-Ig (same clone as 67011-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 67011-1-Ig (PLCG2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67011-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PLCG2 antibody included
  • Featured Product
  • KD/KO验证

PLCG2 Monoclonal antibody, PBS Only

PLCG2 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 67011-1-PBS

产品说明书

CloneNo. 2F8H5

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, ELISA

别名

Phospholipase C IV, Phospholipase C gamma 2, Phosphoinositide phospholipase C-gamma-2, EC:3.1.4.11, 2F8H5

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PLCG2 Ready-To-Use IHC Kit. PLCG2 primary antibody included.

产品信息

67011-1-PBS targets PLCG2 in WB, IHC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human
免疫原 PLCG2 fusion protein Ag24355 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 phospholipase C, gamma 2 (phosphatidylinositol-specific)
别名 Phospholipase C IV, Phospholipase C gamma 2, Phosphoinositide phospholipase C-gamma-2, EC:3.1.4.11, 2F8H5
计算分子量 148 kDa
观测分子量 148 kDa
GenBank蛋白编号BC007565
基因名称 PLCG2
Gene ID (NCBI) 5336
RRIDAB_2882328
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP16885
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Phospholipase C-gamma2 (PLCG2) is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor.IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.