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PLCZ1 Recombinant antibody

PLCZ1 Recombinant Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

ELISA

Conjugate

Unconjugated

CloneNo.

230187E2

Cat No : 83090-1-RR

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Synonyms

Phospholipase C zeta 1, Phosphoinositide phospholipase C-zeta-1, NYD SP27, EC:3.1.4.11, 230187E2

验证数据展示

  • Affinity and Kinetic Characterization of 83090-1-RR

    Affinity and Kinetic Characterization of 83090-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83090-1-RR against Human PLCZ1 were performed. The affinity constant is 43.4 nM.

产品信息

83090-1-RR targets PLCZ1 in ELISA applications and shows reactivity with human samples.

Tested Applications ELISA Application Description
Tested Reactivity human
Immunogen PLCZ1 fusion protein Ag26899 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name phospholipase C, zeta 1
Synonyms Phospholipase C zeta 1, Phosphoinositide phospholipase C-zeta-1, NYD SP27, EC:3.1.4.11, 230187E2
Calculated Molecular Weight 608 aa, 70 kDa
GenBank Accession NumberBC125067
Gene Symbol PLCZ1
Gene ID (NCBI) 89869
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ86YW0
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Phospholipase C zeta1 (Plcz1) was known to be a physiological factor in sperm that activates oocytes to complete meiosis by triggering Ca2+ oscillations after fertilisation (PMID: 36613757). PLCZ1 is considered a major sperm-borne oocyte activation factor. After gamete fusion, PLCZ1 triggers calcium oscillations in the oocyte, resulting in oocyte activation (PMID: 38133249).