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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84888-4-RR (same clone as 84888-4-PBS)

    WB analysis using 84888-4-RR (same clone as 84888-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84888-4-RR (PLSCR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84888-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84888-4-RR

    Affinity and Kinetic Characterization of 84888-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84888-4-RR against Human PLSCR1 were performed. The affinity constant is 0.377 nM.

PLSCR1 Recombinant antibody, PBS Only

PLSCR1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84888-4-PBS

Print datasheet

CloneNo. 242372B2

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

phospholipid scramblase 1, MMTRA1B, Mg(2+)-dependent nuclease, EC:3.1.-.-, Ca(2+)-dependent phospholipid scramblase 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PLSCR1 Ready-To-Use IHC Kit. PLSCR1 primary antibody included.

产品信息

84888-4-PBS targets PLSCR1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen PLSCR1 fusion protein Ag2172 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name phospholipid scramblase 1
Synonyms phospholipid scramblase 1, MMTRA1B, Mg(2+)-dependent nuclease, EC:3.1.-.-, Ca(2+)-dependent phospholipid scramblase 1
Calculated Molecular Weight 318 aa, 35 kDa
Observed Molecular Weight34 kDa
GenBank Accession NumberBC021100
Gene Symbol PLSCR1
Gene ID (NCBI) 5359
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO15162
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PLSCR1 (Phospholipid scramblase 1) is a member of the family of membrane proteins that mediate the transbilayer movement of phospholipids ("scrambling") in a Ca2+ dependent manner, which was identified as an a type II transmembrane protein involved in the calcium-dependent, nonspecific, rapid redistribution of phospholipids. A cysteine-rich palmitoylation motif [184CCCPCC189] of PLSCR1, a thioester linkage to the sulfhydryl groups of cysteines, controls the transportation of PLSCR1 to the cell membrane or nucleus (PMID: 32292520). PLSCR1 is strongly expressed in response to interferon (IFN) treatment and viral infection (PMID: 35138119, 23487022).