PNRC2 Polyclonal antibody
PNRC2 Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
ELISA and More (3)
Conjugate
Unconjugated
验证数据展示
产品信息
51050-1-AP targets PNRC2 in WB, IHC, ChIP, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | ELISA Application Description |
| Cited Applications | WB, IHC, ChIP |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Immunogen | PNRC2 fusion protein Ag0099 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | proline-rich nuclear receptor coactivator 2 |
| Synonyms | Proline-rich nuclear receptor coactivator 2, HSPC208 |
| Calculated Molecular Weight | 16 kDa |
| Observed Molecular Weight | 25 kDa |
| GenBank Accession Number | BC001959 |
| Gene Symbol | PNRC2 |
| Gene ID (NCBI) | 55629 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NPJ4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PNRC2 belongs to the PNRC family and PNRC2 subfamily. It is Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. It is required for UPF1/RENT1 localization to the P-body. PNRC2 also acts as a nuclear receptor coactivator. It may play a role in controlling the energy balance between energy storage and energy expenditure. (PMID:19150429) PNRC2 functions as a coactivator of several nuclear receptors, including ERRa, and participates in the activation of aromatase in conjunction with ERRa. Growth factor signaling promotes PELP1 recruitment to the aromatase chromatin and its formation of a complex with ERRa and PNRC2.(PMID:18079323)