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  • Featured Product
  • KD/KO Validated

PPM1K Polyclonal antibody, PBS Only

PPM1K Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14573-1-PBS

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Synonyms

验证数据展示

  • WB analysis of human brain using 14573-1-AP (same clone as 14573-1-PBS)

    WB analysis of human brain using 14573-1-AP (same clone as 14573-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 14573-1-AP (PPM1K antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14573-1-PBS in a different storage buffer formulation.

  • IHC staining of human gliomas using 14573-1-AP (same clone as 14573-1-PBS)

    IHC staining of human gliomas using 14573-1-AP (same clone as 14573-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas using 14573-1-AP (PPM1K antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14573-1-PBS in a different storage buffer formulation.

  • IHC staining of human gliomas using 14573-1-AP (same clone as 14573-1-PBS)

    IHC staining of human gliomas using 14573-1-AP (same clone as 14573-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas using 14573-1-AP (PPM1K antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14573-1-PBS in a different storage buffer formulation.

产品信息

14573-1-PBS targets PPM1K in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen PPM1K fusion protein Ag5660 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name protein phosphatase 1K (PP2C domain containing)
Synonyms
Calculated Molecular Weight 41 kDa
Observed Molecular Weight30-40 kDa
GenBank Accession NumberBC037552
Gene Symbol PPM1K
Gene ID (NCBI) 152926
RRIDAB_2252953
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8N3J5
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Protein phosphatase, Mg2+/Mn2+ dependent 1K (PPM1K), is a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. PPMiK, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.PPM1K is essential for the regulation and nutrient-induced activation of the branched-chain alpha-keto acid dehydrogenase complex (BCKD or BCKDC), which catalyzes the breakdown of branched-chain amino acids (BCAA).