PPP2CA Recombinant antibody

PPP2CA Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 84155-2-RR

产品说明书

CloneNo. 241112A6

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat, pig

应用

WB, ELISA

241112A6, EC:3.1.3.16, PP2A alpha, PP2A-alpha, PP2Ac

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHeLa cells, Jurkat cells, MCF-7 cells, mouse brain tissue, pig brain tissue, rat brain tissue
Planning an IHC experiment? We recommend our IHCeasy PPP2CA Ready-To-Use IHC Kit. PPP2CA primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84155-2-RR targets PPP2CA in WB, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原 PPP2CA fusion protein Ag4294 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
别名 241112A6, EC:3.1.3.16, PP2A alpha, PP2A-alpha, PP2Ac
计算分子量 309 aa, 36 kDa
观测分子量 36 kDa
GenBank蛋白编号BC031696
基因名称 PPP2CA
Gene ID (NCBI) 5515
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP67775
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PPP2CA, also named as RP-C and PP2A-alpha, belongs to the PPP phosphatase family and PP-1 subfamily. PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. PP2A activity was modestly decreased in AML patients harboring C-KIT/WT.PP2A is a target for C-KIT/TKD and implicated the potential efficacy of therapies targeting PP2A in such AML in future.

实验方案

Product Specific Protocols
WB protocol for PPP2CA antibody 84155-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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