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PPYR1 Polyclonal antibody

PPYR1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 21654-1-AP

Print datasheet

Synonyms

Neuropeptide Y receptor type 4, PP1, PPYR1, Y4

验证数据展示

  • IHC staining of human small intestine using 21654-1-AP

    IHC staining of human small intestine using 21654-1-AP

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 21654-1-AP (PPYR1 antibody) at dilution of 1:200 (under 40x lens).

  • IHC staining of human small intestine using 21654-1-AP

    IHC staining of human small intestine using 21654-1-AP

    Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 21654-1-AP (PPYR1 Antibody) at dilution of 1:50 (under 10x lens).

经过测试的应用

Positive IHC detected inhuman small intestine tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

21654-1-AP targets PPYR1 in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen PPYR1 fusion protein Ag16374 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name pancreatic polypeptide receptor 1
Synonyms Neuropeptide Y receptor type 4, PP1, PPYR1, Y4
Calculated Molecular Weight 375 aa, 42 kDa
GenBank Accession NumberBC096238
Gene Symbol PPYR1
Gene ID (NCBI) 5540
RRIDAB_2878900
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP50391
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PPYR1 (pancreatic polypeptide receptor 1), also known as NPY4R, is a member of the G-protein coupled receptor 1 family. PPYR1 is a receptor for the PP-fold peptides (pancreatic polypeptide, peptide YY, and neuropeptide Y) and pancreatic polypeptide is the preferred ligand (PMID: 12626767). It may be regulating central nervous system, cardiovascular and gastrointestinal function. It has been reported that PPYR1 gene is a key regulator of energy homeostasis (PMID: 12000791). PPYR1 gene copy number gain has been associated with lower body mass index (BMI) (PMID: 19229253).

实验方案

Product Specific Protocols
IHC protocol for PPYR1 antibody 21654-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols