PRKCB Monoclonal antibody, PBS Only
PRKCB Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat, pig, rabbit
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
4B7A1
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy PRKCB Ready-To-Use IHC Kit. PRKCB primary antibody included.
产品信息
68620-1-PBS targets PRKCB in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat, pig, rabbit |
Immunogen | PRKCB fusion protein Ag33693 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | protein kinase C, beta |
Synonyms | PKC beta, PKCB, PKC B, pan-PKC, EC:2.7.11.13 |
Calculated Molecular Weight | 673 aa, 77 kDa |
Observed Molecular Weight | 77 kDa |
GenBank Accession Number | BC036472 |
Gene Symbol | PRKCB |
Gene ID (NCBI) | 5579 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P05771 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. Protein kinase Cs (PKCs) are signaling molecules that play key roles in many cellular processes, including secretion, gene expression, proliferation, and muscle contraction. The PKC family is broadly divided into three subgroups: classical, novel, and atypical PKCs. These subgroups differ in both protein sequences and mechanistic requirements for catalytic activity. PKC beta is one of the PKC family members. PKC beta has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress.