验证数据展示
经过测试的应用
| Positive WB detected in | ARPE-19 cells, rabbit eye tissue, hTERT-RPE1 cells, rat eye tissue, mouse eye tissue, rabbit retina tissue, rat retina tissue, mouse retina tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
68780-1-Ig targets PRPH2 in WB, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat, rabbit |
| 免疫原 | PRPH2 fusion protein Ag12555 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2a |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | peripherin 2 (retinal degeneration, slow) |
| 别名 | Peripherin-2, Peripherin2, Peripherin 2, AVMD, AOFMD |
| 计算分子量 | 346 aa, 39 kDa |
| 观测分子量 | 35-39 kDa |
| GenBank蛋白编号 | BC074720 |
| 基因名称 | PRPH2 |
| Gene ID (NCBI) | 5961 |
| RRID | AB_3670425 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P23942 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for PRPH2 antibody 68780-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
