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PRPH2 Recombinant antibody, PBS Only

PRPH2 Uni-rAbTM Recombinant Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242170F4

Cat no : 85043-1-PBS

Print datasheet

Synonyms

Peripherin-2, Peripherin2, Peripherin 2, AVMD, AOFMD

验证数据展示

  • WB analysis using 85043-1-RR (same clone as 85043-1-PBS)

    WB analysis using 85043-1-RR (same clone as 85043-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85043-1-RR (PRPH2 antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85043-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse eye using 85043-1-RR (same clone as 85043-1-PBS)

    IHC staining of mouse eye using 85043-1-RR (same clone as 85043-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse eye tissue slide using 85043-1-RR (PRPH2 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85043-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse eye using 85043-1-RR (same clone as 85043-1-PBS)

    IF Staining of mouse eye using 85043-1-RR (same clone as 85043-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse eye tissue using PRPH2 antibody (85043-1-RR, Clone: 242170F4 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85043-1-PBS in a different storage buffer formulation.

产品信息

85043-1-PBS targets PRPH2 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen PRPH2 fusion protein Ag12555 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name peripherin 2 (retinal degeneration, slow)
Synonyms Peripherin-2, Peripherin2, Peripherin 2, AVMD, AOFMD
Calculated Molecular Weight 346 aa, 39 kDa
Observed Molecular Weight30-40 kDa
GenBank Accession NumberBC074720
Gene Symbol PRPH2
Gene ID (NCBI) 5961
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP23942
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).