验证数据展示
产品信息
85043-2-PBS targets PRPH2 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, rat |
| 免疫原 | PRPH2 fusion protein Ag12555 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | peripherin 2 (retinal degeneration, slow) |
| 别名 | Peripherin-2, Peripherin2, Peripherin 2, AVMD, AOFMD |
| 计算分子量 | 346 aa, 39 kDa |
| 观测分子量 | 35-39 kDa |
| GenBank蛋白编号 | BC074720 |
| 基因名称 | PRPH2 |
| Gene ID (NCBI) | 5961 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P23942 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in maintaining the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).