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PRR11 Polyclonal antibody

PRR11 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 27422-1-AP

Print datasheet

Synonyms

Proline rich protein 11, proline rich 11

验证数据展示

  • WB analysis using 27422-1-AP

    WB analysis using 27422-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 27422-1-AP (PRR11 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inA549 cells, HeLa cells, L02 cells, MCF-7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:5000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

27422-1-AP targets PRR11 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen PRR11 fusion protein Ag26636 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name proline rich 11
Synonyms Proline rich protein 11, proline rich 11
Calculated Molecular Weight 360 aa, 40 kDa
Observed Molecular Weight38 kDa
GenBank Accession NumberBC008669
Gene Symbol PRR11
Gene ID (NCBI) 55771
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96HE9
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PRR11, or Proline-rich protein 11, is a protein-coding gene situated on chromosome 17q22-23, which plays a significant role in various cellular processes. The protein itself is composed of a nuclear localization signal (NLS), two proline-rich regions (PRs), and a zinc finger domain (ZFD) (PMID: 36551227). PRR11 has been implicated in the regulation of cell cycle, and it is involved in multiple aspects of cancer biology, including proliferation, migration, invasion, cell-cycle progression, apoptosis, autophagy, and chemotherapy resistance. It serves as a prognostic indicator in certain human cancers and is considered a potential target for therapeutic interventions (PMID: 36739300).

实验方案

Product Specific Protocols
WB protocol for PRR11 antibody 27422-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols