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PRRG2 Polyclonal antibody

PRRG2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 11618-1-AP

Print datasheet

Synonyms

Transmembrane gamma-carboxyglutamic acid protein 2, TMG2, Proline-rich Gla protein 2, Proline-rich gamma-carboxyglutamic acid protein 2, PRGP2

验证数据展示

  • WB analysis using 11618-1-AP

    WB analysis using 11618-1-AP

    37°C incubated mouse kidney tissue and mouse kidney tissue were subjected to SDS PAGE followed by western blot with 11618-1-AP (PRRG2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse kidney tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11618-1-AP targets PRRG2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen PRRG2 fusion protein Ag2197 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name proline rich Gla (G-carboxyglutamic acid) 2
Synonyms Transmembrane gamma-carboxyglutamic acid protein 2, TMG2, Proline-rich Gla protein 2, Proline-rich gamma-carboxyglutamic acid protein 2, PRGP2
Calculated Molecular Weight 179 aa, 20 kDa
Observed Molecular Weight16-22 kDa
GenBank Accession NumberBC026032
Gene Symbol PRRG2
Gene ID (NCBI) 5639
RRIDAB_2171684
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO14669
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Proline-rich Gla protein 2 (PRRG2) represents one of the four known transmembrane-carboxyglutamic acid proteins in vertebrates. As a founding member of the vitamin K-dependent, single-pass integral membrane protein family, PRRG2 is characterized by an extracellular N-terminus consisting of approximately 45 amino acids rich in Gla, as well as a conserved Pro/Leu-Pro-xaa-Tyr (PY) motif proximal to its C-terminus. PRRG2 primarily localizes to the cell surface, where the Gla domain is exposed extracellularly, serving as a pivotal gene node with positive autoregulatory function that plays a critical role in maintaining human hemostasis (PMID: 38227081). The calculated molecular weight of PRRG2 is usually approximately 22 kda.

实验方案

Product Specific Protocols
WB protocol for PRRG2 antibody 11618-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols