验证数据展示
产品信息
17171-1-PBS targets PSCA in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | PSCA fusion protein Ag10710 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | prostate stem cell antigen |
别名 | |
计算分子量 | 123 aa, 13 kDa |
观测分子量 | 36 kDa |
GenBank蛋白编号 | BC023582 |
基因名称 | PSCA |
Gene ID (NCBI) | 8000 |
RRID | AB_2172635 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | O43653 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Prostate stem cell antigen (PSCA) is a protein composed of 123 amino acid residues. PSCA belongs to the LY-6/Thy-1 family of cell surface antigens. It is highly expressed in normal prostate and further up-regulated in prostate cancer, as well as non-prostatic malignancies including gastric cancer. PSCA plays a critical role in cell adhesion, proliferation, and survival. The obasrved MW of PSCA is between 36 to 40 kDa in paper (PMID: 11309275).