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验证数据展示

  • WB analysis using 85352-2-RR (same clone as 85352-2-PBS)

    WB analysis using 85352-2-RR (same clone as 85352-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85352-2-RR (PTK6/BRK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85352-2-PBS in a different storage buffer formulation.

  • IF Staining of A549 using 85352-2-RR (same clone as 85352-2-PBS)

    IF Staining of A549 using 85352-2-RR (same clone as 85352-2-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed A549 cells using PTK6 antibody (85352-2-RR, Clone: 242647F4 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85352-2-PBS in a different storage buffer formulation.

PTK6/BRK Recombinant antibody, PBS Only

PTK6/BRK Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 85352-2-PBS

产品说明书

CloneNo. 242647F4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

PTK6, BRK, 242647F4, Protein-tyrosine kinase 6, Protein tyrosine kinase 6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PTK6/BRK Ready-To-Use IHC Kit. PTK6/BRK primary antibody included.

产品信息

85352-2-PBS targets PTK6/BRK in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 PTK6 protein tyrosine kinase 6
别名 PTK6, BRK, 242647F4, Protein-tyrosine kinase 6, Protein tyrosine kinase 6
计算分子量 52 kDa
观测分子量 52 kDa
GenBank蛋白编号BC035843
基因名称 PTK6
Gene ID (NCBI) 5753
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13882
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BRK, also named as PTK6 and FLJ42088, is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. PTK6 can phosphorylate KHDRBS1, KHDRBS2, KHDRBS3 and STAP2/BKS. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. This antibody is specific to PTK6.