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Prothymosin Alpha Polyclonal antibody

Prothymosin Alpha Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 10480-1-AP

Print datasheet

Synonyms

Prothymosin alpha, prothymosin, alpha, PTMA, TMSA

验证数据展示

  • IHC staining of human lymphoma using 10480-1-AP

    IHC staining of human lymphoma using 10480-1-AP

    Immunohistochemical analysis of paraffin-embedded human lymphoma using 10480-1-AP (Prothymosin alpha antibody) at dilution of 1:100 (under 25x lens).

经过测试的应用

Positive IHC detected inhuman lymphoma tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10480-1-AP targets Prothymosin Alpha in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen Prothymosin Alpha fusion protein Ag0732 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name prothymosin, alpha
Synonyms Prothymosin alpha, prothymosin, alpha, PTMA, TMSA
Calculated Molecular Weight 12 kDa
GenBank Accession NumberBC003510
Gene Symbol Prothymosin Alpha/PTMA
Gene ID (NCBI) 5757
RRIDAB_2174388
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP06454
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels. Extensive research on PTMA showed that it is of clinical significance and potential medical use as they may serve as a molecular marker for cancer prognosis and/or as therapeutic agents for treating immunodeficiencies, autoimmune diseases and malignancies.

实验方案

Product Specific Protocols
IHC protocol for Prothymosin Alpha antibody 10480-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols