验证数据展示
发表文章中的应用
| WB | See 1 publications below |
产品信息
11131-1-AP targets PTPN4 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human |
| 文献引用反应性 | human |
| 免疫原 | PTPN4 fusion protein Ag1585 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| 别名 | Tyrosine protein phosphatase non receptor type 4, PTPN 4, PTPase-MEG1, PTN4, Protein-tyrosine phosphatase MEG1 |
| 计算分子量 | 106 kDa |
| 观测分子量 | 106 kDa |
| GenBank蛋白编号 | BC010674 |
| 基因名称 | PTPN4 |
| Gene ID (NCBI) | 5775 |
| RRID | AB_2173540 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P29074 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PTPN4 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.