验证数据展示
经过测试的应用
| Positive WB detected in | rat brain tissue, pig brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
83695-1-RR targets PTPN4 in WB, ELISA applications and shows reactivity with human, rat, pig samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, rat, pig |
| 免疫原 | PTPN4 fusion protein Ag1585 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| 别名 | PTPN 4, PTPase-MEG1, PTN4, Protein-tyrosine phosphatase MEG1, EC:3.1.3.48 |
| 计算分子量 | 106 kDa |
| 观测分子量 | 106 kDa |
| GenBank蛋白编号 | BC010674 |
| 基因名称 | PTPN4 |
| Gene ID (NCBI) | 5775 |
| RRID | AB_3671298 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P29074 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PTPN4 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for PTPN4 antibody 83695-1-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |