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验证数据展示

  • WB analysis of pig spleen using 68635-1-Ig

    WB analysis of pig spleen using 68635-1-Ig

    pig spleen tissue were subjected to SDS PAGE followed by western blot with 68635-1-Ig (PTPRH antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

  • WB analysis of A431 using 68635-1-Ig

    WB analysis of A431 using 68635-1-Ig

    A431 cells were subjected to SDS PAGE followed by western blot with 68635-1-Ig (PTPRH antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

PTPRH Monoclonal antibody

PTPRH Monoclonal Antibody for WB, ELISA
Cat No. 68635-1-Ig

产品说明书

CloneNo. 3C6E8

宿主/亚型

Mouse / IgG1

种属反应性

human, pig

应用

WB, ELISA

别名

SAP1, SAP 1, R PTP H, 3C6E8

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inpig spleen tissue, A431 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

68635-1-Ig targets PTPRH in WB, ELISA applications and shows reactivity with human, pig samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, pig
免疫原 PTPRH fusion protein Ag17351 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 protein tyrosine phosphatase, receptor type, H
别名 SAP1, SAP 1, R PTP H, 3C6E8
计算分子量 1115 aa, 122 kDa
观测分子量200-210 kDa
GenBank蛋白编号BC111716
基因名称 PTPRH
Gene ID (NCBI) 5794
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ9HD43
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PTPRH, also known as SAP-1 (Stomach Cancer-Associated Protein-Tyrosine Phosphatase-1), is a member of the protein tyrosine phosphatase (PTP) family. These enzymes regulate cellular signaling by dephosphorylating tyrosine residues on proteins, counterbalancing kinase activity (PMID: 11278335). PTPRH is classified as a receptor-type PTP, characterized by an extracellular domain, a transmembrane region, and intracellular catalytic domains. In colorectal, gastric, and hepatocellular cancers, PTPRH is often upregulated and linked to poor prognosis (PMID: 12101188). Paradoxically, it may suppress tumorigenesis in other contexts by stabilizing cell adhesion. Overexpression in certain cancers suggests utility as a diagnostic or prognostic marker. The molecular weight of PTPRH is 122 kDa, it is reported that it can form a dimer with a molecular weight of 210 kDa (PMID:15850787).

实验方案

Product Specific Protocols
WB protocol for PTPRH antibody 68635-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols