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验证数据展示

  • WB analysis using 31720-1-AP

    WB analysis using 31720-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

  • WB analysis using 31720-1-AP

    WB analysis using 31720-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

PTPRS Polyclonal antibody

PTPRS Polyclonal Antibody for WB, ELISA
Cat No. 31720-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, ELISA

别名

Receptor-type tyrosine-protein phosphatase sigma, Receptor-type tyrosine-protein phosphatase S, R PTP sigma, R PTP S, PTPSIGMA

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inHEK-293 cells, A431 cells, HeLa cells, SH-SY5Y cells, mouse brain tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31720-1-AP targets PTPRS in WB, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 protein tyrosine phosphatase, receptor type, S
别名 Receptor-type tyrosine-protein phosphatase sigma, Receptor-type tyrosine-protein phosphatase S, R PTP sigma, R PTP S, PTPSIGMA
计算分子量217 kDa
观测分子量140 kDa
GenBank蛋白编号NM_002850
基因名称 PTPRS
Gene ID (NCBI) 5802
RRIDAB_3670097
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ13332
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protein tyrosine phosphatase receptor type S (PTPRS, also known as R-PTP-S, PTPSIGMA, and R-PTP-sigma) is an integral membrane protein. It can promote oligomerization by binding to large heparan sulfate proteoglycan structures, and interact with NTRK1/3, PPFIA1/2/3 (PMID: 25385546; 8524829; 9624153). The non-glycosylated molecular weight of PTPRS is 214 kDa, and the extracellular domain can be cleaved near the cell membrane by an endoprotease to generate a glycated 140 kDa protein. Variations and mutations of PTPRS are associated with Alzheimer's disease and cholangiocarcinoma (PMID: 38766183; 35991009).

实验方案

Product Specific Protocols
WB protocol for PTPRS antibody 31720-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols