PUMA BH3 acetate

PUMA BH3 acetate (PUMA BH3 Free base) 是一种 p53 凋亡阳性调节因子 (PUMA) BH3 结构域多肽,可作为 Bak 的直接激活剂,Kd 为 26 nM。

CAS号

分子式

C130H206N42O45S

主要靶点

BCL

仅限科研使用

Cat No : CM19552

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Synonyms

PUMA BH3 acetate(PUMA BH3 Free base)



产品信息

PUMA BH3 acetate is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of 26 nM.

CAS号
分子式 C130H206N42O45S
主要靶点 BCL
主要通路 凋亡
分子量 3109.35
纯度 96.64%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 PUMA BH3 acetate(PUMA BH3 Free base)

靶点活性

p53:26 nM(Kd)

参考文献

1.Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.

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The dilution calculator equation

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