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  • Featured Product
  • KD/KO Validated

Periostin Polyclonal antibody, PBS Only

Periostin Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19899-1-PBS

Print datasheet

Synonyms

PDLPOSTN, Osteoblast-specific factor 2, Osteoblast specific factor 2, OSF-2, OSF2

验证数据展示

  • IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

    IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Periostin antibody included
  • IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

    IHC staining of human colon using 19899-1-AP (same clone as 19899-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19899-1-AP (Periostin antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 19899-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Periostin antibody included
Planning an IHC experiment? We recommend our IHCeasy Periostin Ready-To-Use IHC Kit. Periostin primary antibody included.

产品信息

19899-1-PBS targets Periostin in IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Periostin fusion protein Ag13791 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name periostin, osteoblast specific factor
Synonyms PDLPOSTN, Osteoblast-specific factor 2, Osteoblast specific factor 2, OSF-2, OSF2
Calculated Molecular Weight 93 kDa
GenBank Accession NumberBC106710
Gene Symbol Periostin
Gene ID (NCBI) 10631
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ15063
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Periostin (POSTN, PN), originally named as osteoblast-specific factor 2 (OSF-2), is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues, and has a role in bone, tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types, including lung, ovary, breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour, and it is required to allow cancer stem cell maintenance. The isoforms of periostin are between 83 and 93 kDa in mass and differ in their C-terminal sequences, characterized by individual presence or absence of cassette exons 17-21 (UniProtKB/Swiss-Prot,PMID: 21997759).