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Piccolo Polyclonal antibody, PBS Only

Piccolo Polyclonal Antibody for IF-P, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IF-P, Indirect ELISA

Conjugate

Unconjugated

Cat no : 18156-1-PBS

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Synonyms

验证数据展示

  • IF Staining of mouse brain using 18156-1-AP (same clone as 18156-1-PBS)

    IF Staining of mouse brain using 18156-1-AP (same clone as 18156-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using Piccolo antibody (18156-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 18156-1-PBS in a different storage buffer formulation.

产品信息

18156-1-PBS targets Piccolo in IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IF-P, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen Piccolo fusion protein Ag12952 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name piccolo (presynaptic cytomatrix protein)
Synonyms
Calculated Molecular Weight 553 kDa
GenBank Accession NumberBC001304
Gene Symbol Piccolo
Gene ID (NCBI) 27445
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y6V0
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Piccolo is a presynaptic scaffolding protein of the cytomatrix assembled at the active zone (AZ). AZ is a special region of the presynaptic plasma membrane where synaptic vesicles (SVs) fuse. It has been shown that Piccolo affects presynaptic function by negatively regulating SV exocytosis (PMID: 18519737).