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Prohibitin Monoclonal antibody, PBS Only

Prohibitin Monoclonal Antibody for WB,Indirect ELISA,IHC

Host / Isotype

Mouse / IgG1

Reactivity

human, pig, rat

Applications

WB,Indirect ELISA,IHC

Conjugate

Unconjugated

CloneNo.

4D3G5

Cat No : 60092-1-PBS

Print datasheet

Synonyms

Cell and organelle markers, Mitochondria Marker, Mitochondrial Marker, Mitochondrion Marker, PHB, PHB1, prohibitin

验证数据展示

  • WB analysis using 60092-1-Ig (same clone as 60092-1-PBS)

    WB analysis using 60092-1-Ig (same clone as 60092-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60092-1-Ig (Prohibitin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60092-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 60092-1-Ig (Prohibitin antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60092-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 60092-1-Ig (Prohibitin antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60092-1-PBS in a different storage buffer formulation.

产品信息

60092-1-PBS targets Prohibitin in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig, rat samples.

Tested Applications WB,Indirect ELISA,IHC Application Description
Tested Reactivity human, pig, rat
Immunogen Prohibitin fusion protein Ag1240 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name prohibitin
Synonyms Cell and organelle markers, Mitochondria Marker, Mitochondrial Marker, Mitochondrion Marker, PHB, PHB1, prohibitin
Calculated Molecular Weight 30 kDa
Observed Molecular Weight 30 kDa
GenBank Accession NumberBC013401
Gene Symbol PHB
Gene ID (NCBI) 5245
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP35232
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis (PMID: 20840588 ). This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription (PMID: 18558096). Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis (PMID: 24402549).