• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 60092-1-Ig (same clone as 60092-1-PBS)

    WB analysis using 60092-1-Ig (same clone as 60092-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60092-1-Ig (Prohibitin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60092-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 60092-1-Ig (Prohibitin antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60092-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Prohibitin/PHB1 antibody included
  • IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    IHC staining of human liver using 60092-1-Ig (same clone as 60092-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 60092-1-Ig (Prohibitin antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60092-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with Prohibitin/PHB1 antibody included

Prohibitin Monoclonal antibody, PBS Only

Prohibitin Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60092-1-PBS

产品说明书

CloneNo. 4D3G5

宿主/亚型

Mouse / IgG1

种属反应性

human, pig, rat

应用

WB, IHC, Indirect ELISA

别名

Cell and organelle markers, Mitochondria Marker, Mitochondrial Marker, Mitochondrion Marker, PHB, PHB1, prohibitin

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy Prohibitin/PHB1 Ready-To-Use IHC Kit. Prohibitin/PHB1 primary antibody included.

产品信息

60092-1-PBS targets Prohibitin in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, pig, rat
免疫原 Prohibitin fusion protein Ag1240 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 prohibitin
别名 Cell and organelle markers, Mitochondria Marker, Mitochondrial Marker, Mitochondrion Marker, PHB, PHB1, prohibitin
计算分子量 30 kDa
观测分子量 30 kDa
GenBank蛋白编号BC013401
基因名称 Prohibitin
Gene ID (NCBI) 5245
RRIDAB_2252403
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP35232
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis (PMID: 20840588 ). This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription (PMID: 18558096). Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis (PMID: 24402549).