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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68394-1-Ig (same clone as 68394-1-PBS)

    WB analysis using 68394-1-Ig (same clone as 68394-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68394-1-Ig (Protein Z antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68394-1-PBS in a different storage buffer formulation.

Protein Z Monoclonal antibody, PBS Only

Protein Z Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68394-1-PBS

产品说明书

CloneNo. 2A1D3

宿主/亚型

Mouse / IgG2a

种属反应性

Human

应用

WB, Indirect ELISA

别名

PROZ, PZ, Vitamin K dependent protein Z

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68394-1-PBS targets Protein Z in WB, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human
免疫原 Protein Z fusion protein Ag13051 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 protein Z, vitamin K-dependent plasma glycoprotein
别名 PROZ, PZ, Vitamin K dependent protein Z
计算分子量 400 aa, 45 kDa
观测分子量 45-47 kDa, 27 kDa
GenBank蛋白编号BC074906
基因名称 PROZ
Gene ID (NCBI) 8858
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP22891
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Protein Z (PZ, PROZ) is a vitamin K-dependent plasma protein that serves as a cofactor for activated factor X inhibition by the PZ-dependent protease inhibitor (PMID: 16938126). Reduced circulating levels of PZ have been suggested to play a role in the occurrence of bleeding (PMID: 7495103) and deep vein thrombosis (DVT) (PMID: 10829076), as well as in unexplained abortions with early fetal loss (PMID: 11895801), late fetal demise and intrauterine growth restriction (PMID: 16260213), acute coronary syndromes (PMID: 14652653), and stroke (PMID: 11570404). In addition, PZ may be a biomarker for the early diagnosis of pancreatic cancer (PMID: 31025496). It has two isoforms with molecular weights of 44 kDa and 47 kDa.