验证数据展示
发表文章中的应用
| WB | See 2 publications below |
| IF | See 2 publications below |
产品信息
60057-1-Ig targets Rab18 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IF |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | mouse, monkey |
| 免疫原 | Rab18 fusion protein Ag1841 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | RAB18, member RAS oncogene family |
| 别名 | RAB18, RAB18LI1, Ras related protein Rab 18 |
| 计算分子量 | 206 aa, 23 kDa |
| GenBank蛋白编号 | BC015014 |
| 基因名称 | RAB18 |
| Gene ID (NCBI) | 22931 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Caprylic acid/ammonium sulfate precipitation |
| UNIPROT ID | Q9NP72 |
| 储存缓冲液 | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
RAB18 is a member of a family of Ras-related small GTPases. RAB18 plays a role in apical endocytosis/recycling, and may be implicated in transport between the plasma membrane and early endosomes. It also plays a key role in eye and brain development and neurodegeneration. Defects in RAB18 are associated with Warburg micro syndrome type 3.
实验方案
| Product Specific Protocols | |
|---|---|
| IF protocol for Rab18 antibody 60057-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Redox Biol Homocysteine promotes hepatic steatosis by activating the adipocyte lipolysis in a HIF1α-ERO1α-dependent oxidative stress manner. | ||
J Cell Biol Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions. | ||
Mol Neurobiol Rab18 Collaborates with Rab7 to Modulate Lysosomal and Autophagy Activities in the Nervous System: an Overlapping Mechanism for Warburg Micro Syndrome and Charcot-Marie-Tooth Neuropathy Type 2B. |
