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验证数据展示

  • WB analysis using 31303-1-AP

    WB analysis using 31303-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31303-1-AP (RAB21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

  • WB analysis using 31303-1-AP

    WB analysis using 31303-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31303-1-AP (RAB21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

RAB21 Polyclonal antibody

RAB21 Polyclonal Antibody for WB, ELISA
Cat No. 31303-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

Ras related protein Rab 21, KIAA0118

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inMDA-MB-231 cells, HeLa cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31303-1-AP targets RAB21 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 RAB21 fusion protein Ag35291 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 RAB21, member RAS oncogene family
别名 Ras related protein Rab 21, KIAA0118
计算分子量24 kDa
观测分子量24 kDa
GenBank蛋白编号NM_014999
基因名称 RAB21
Gene ID (NCBI) 23011
RRIDAB_3669940
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ9UL25
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Small GTPase Rab21 is a ubiquitously expressed and has recently been shown to associate with the α tails of several integrins via the shared conserved membrane proximal sequence, thus regulating cell adhesion and migration via controlling the endo/exocytic trafficking of most integrin heterodimers (PMID: 18804435). Rab21 is required for the pruning of the immature neurites during the multipolar-to-bipolar transition (PMID: 36683567). Knock down of Rab21 impairs integrin-mediated cell adhesion and motility, whereas its overexpression stimulates cell migration and cancer cell adhesion to collagen and human bone (PMID: 16754960).

实验方案

Product Specific Protocols
WB protocol for RAB21 antibody 31303-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols