验证数据展示
产品信息
68603-1-PBS targets RAB38 in WB, Indirect ELISA applications and shows reactivity with Human samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | Human |
| Immunogen | RAB38 fusion protein Ag26440 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | RAB38, member RAS oncogene family |
| Synonyms | Melanoma antigen NY MEL 1, NY MEL 1, RAB38, Ras related protein Rab 38, rrGTPbp |
| Calculated Molecular Weight | 211 aa, 24 kDa |
| Observed Molecular Weight | 24 kDa |
| GenBank Accession Number | BC015808 |
| Gene Symbol | RAB38 |
| Gene ID (NCBI) | 23682 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P57729 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The RAB family of small GTPases is part of the Ras protein superfamily and is primarily responsible for regulating intracellular vesicle transport and migration. RAB38 is a recently identified member of the RAB family of proteins and its expression is tissue-specific. RAB38 is predominantly expressed in melanocytes and melanoma tissues, but not in other normal tissues, serving as a melanocyte differentiation antigen. RAB38 has also been reported to be upregulated in glioblastoma, and high levels of its expression are associated with a poor prognosis and enhanced cell migration.
