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RAB3GAP2 Monoclonal antibody, PBS Only

RAB3GAP2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3A4A1

Cat no : 66648-1-PBS

Print datasheet

Synonyms

DKFZp434D245, FLJ14579, KIAA0839, p150, Rab3 GAP p150, Rab3 GAP regulatory subunit, RAB3 GAP150, RAB3GAP150, RAB3GAP2, RGAP iso

验证数据展示

  • WB analysis using 66648-1-Ig (same clone as 66648-1-PBS)

    WB analysis using 66648-1-Ig (same clone as 66648-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66648-1-Ig (RAB3GAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66648-1-PBS in a different storage buffer formulation.

产品信息

66648-1-PBS targets RAB3GAP2 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen RAB3GAP2 fusion protein Ag20254 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name RAB3 GTPase activating protein subunit 2 (non-catalytic)
Synonyms DKFZp434D245, FLJ14579, KIAA0839, p150, Rab3 GAP p150, Rab3 GAP regulatory subunit, RAB3 GAP150, RAB3GAP150, RAB3GAP2, RGAP iso
Calculated Molecular Weight 1393 aa, 156 kDa
Observed Molecular Weight 150 kDa
GenBank Accession NumberBC146760
Gene Symbol RAB3GAP2
Gene ID (NCBI) 25782
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9H2M9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RAB3GAP2, also known as RAB3-GAP150, belongs to the Rab3-GAP regulatory subunit family. Rab3 GAP consists of two subunits: the catalytic subunit p130 and the noncatalytic subunit p150. Rab3 GAP is ubiquitously expressed and enriched in the synaptic soluble fraction of brain, consistent with it having a key role in neurodevelopment. RAB3-GAP150 forms the Rab3 GTPase-activating complex with RAB3-GAP130,where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. Defects in RAB3-GAP150 are the cause of Martsolf and Warburg Micro syndrome.