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验证数据展示

  • WB analysis using 60077-1-Ig (same clone as 60077-1-PBS)

    WB analysis using 60077-1-Ig (same clone as 60077-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60077-1-Ig (RAC2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

    IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RAC2 antibody included
  • IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

    IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with RAC2 antibody included
  • Featured Product
  • KD/KO验证

RAC2 Monoclonal antibody, PBS Only

RAC2 Monoclonal Antibody for WB, IHC, ELISA
Cat No. 60077-1-PBS

产品说明书

CloneNo. 4C2H6

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA

别名

Ras-related C3 botulinum toxin substrate 2, p21-Rac2, p21 Rac2, HSPC022, Gx

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy RAC2 Ready-To-Use IHC Kit. RAC2 primary antibody included.

产品信息

60077-1-PBS targets RAC2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 RAC2 fusion protein Ag1202 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
别名 Ras-related C3 botulinum toxin substrate 2, p21-Rac2, p21 Rac2, HSPC022, Gx
计算分子量 21 kDa
观测分子量 21 kDa
GenBank蛋白编号BC001485
基因名称 RAC2
Gene ID (NCBI) 5880
RRIDAB_2253445
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP15153
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.