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RAC2 Monoclonal antibody, PBS Only

RAC2 Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

4C2H6

Cat no : 60077-1-PBS

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Synonyms

Ras-related C3 botulinum toxin substrate 2, p21-Rac2, p21 Rac2, HSPC022, Gx



Planning an IHC experiment? We recommend our IHCeasy RAC2 Ready-To-Use IHC Kit. RAC2 primary antibody included.

产品信息

60077-1-PBS targets RAC2 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen RAC2 fusion protein Ag1202 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Synonyms Ras-related C3 botulinum toxin substrate 2, p21-Rac2, p21 Rac2, HSPC022, Gx
Calculated Molecular Weight 21 kDa
Observed Molecular Weight 21 kDa
GenBank Accession NumberBC001485
Gene Symbol RAC2
Gene ID (NCBI) 5880
RRIDAB_2253445
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP15153
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.