RAD52 Monoclonal antibody, PBS Only
RAD52 Monoclonal Antibody for WB,Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat
Applications
WB,Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3H8G9
验证数据展示
产品信息
68283-1-PBS targets RAD52 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, rat samples.
| Tested Applications | WB,Indirect ELISA Application Description |
| Tested Reactivity | Human, mouse, rat |
| Immunogen | RAD52 fusion protein Ag27665 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | RAD52 homolog (S. cerevisiae) |
| Synonyms | RAD52, RAD52 homolog (S. cerevisiae) |
| Calculated Molecular Weight | 46 aa |
| Observed Molecular Weight | 46 kDa |
| GenBank Accession Number | NM_001297419 |
| Gene Symbol | RAD52 |
| Gene ID (NCBI) | 5893 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P43351 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
背景介绍
In Saccharomyces cerevisiae, Rad52 functions as a critical mediator of homologous recombination (HR) by facilitating the loading of Rad51 onto ssDNA. However, in mammalian systems and other vertebrates, BRCA2 is known to function as the primary mediator of RAD51 filament formation, while prior studies have shown a limited role for RAD52 in HR.Additionally, loss of RAD52 has little consequence for cell viability. Recent evidence suggests that RAD52 may provide an alternative mediator pathway to BRCA2 function (PMID: 34928169). Several studies have suggested a link between the functional regulation of RAD52 and the protein modification by a small ubiquitin-like modifier (SUMO), sumoylation may play an important role in the nuclear transport of RAD52 (PMID:20190268). The calculated MW of Rad52 is 46 kDa, 68283-1-Ig can detect the band around 46 kDa.