• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

RAMP3 Polyclonal antibody, PBS Only

RAMP3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11861-1-PBS

Print datasheet

Synonyms

验证数据展示

  • WB analysis using 11861-1-AP (same clone as 11861-1-PBS)

    WB analysis using 11861-1-AP (same clone as 11861-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11861-1-AP (RAMP3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11861-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 11861-1-AP (same clone as 11861-1-PBS)

    IHC staining of human breast cancer using 11861-1-AP (same clone as 11861-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer using 11861-1-AP (RAMP3 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 11861-1-PBS in a different storage buffer formulation.

产品信息

11861-1-PBS targets RAMP3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen RAMP3 fusion protein Ag2438 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name receptor (G protein-coupled) activity modifying protein 3
Synonyms
Calculated Molecular Weight16.5 kDa
Observed Molecular Weight 45-50 kDa
GenBank Accession NumberBC022304
Gene Symbol RAMP3
Gene ID (NCBI) 10268
RRIDAB_2176465
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO60896
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The receptor activity-modifying proteins (RAMPs) and the calcitonin receptor-like receptor (CRLR) are both required to generate adrenomedullin (AM) and calcitonin gene-related peptide (CGRP) receptors. During the process, RAMP3 transports the glycosylated 58-kD CGRPR to the cell surface. The formation of CRLR-RAMP heterodimer is essential for the proper cell surface targeting and pharmacological characteristics of both CGRP and AM receptors.