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RANK/TNFRSF11A Polyclonal antibody

RANK/TNFRSF11A Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 55293-1-AP

Print datasheet

Synonyms

TNFRSF11A, TNR11, Receptor activator of NF-KB, Receptor activator of NF KB, RANK

验证数据展示

  • WB analysis using 55293-1-AP

    WB analysis using 55293-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 55293-1-AP (RANK antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inMJ cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

55293-1-AP targets RANK/TNFRSF11A in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Synonyms TNFRSF11A, TNR11, Receptor activator of NF-KB, Receptor activator of NF KB, RANK
Calculated Molecular Weight 66 kDa
Observed Molecular Weight80-90 kDa
GenBank Accession NumberNM_003839
Gene Symbol TNFRSF11A
Gene ID (NCBI) 8792
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y6Q6
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A, also known as RANK, CD265, and ODFR) is the signaling receptor essential for osteoclast differentiation factor-mediated osteoclastogenesis and is involved in the regulation of interactions between T-cells and dendritic cells (PMID: 9878548). The RANK/RANKL/OPG system is a key regulator in bone resorption, and its dysregulation can lead to pathological bone loss (PMID: 37893470).

实验方案

Product Specific Protocols
WB protocol for RANK/TNFRSF11A antibody 55293-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols