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  • Featured Product
  • KD/KO Validated

RB1CC1 Polyclonal antibody

RB1CC1 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB,ELISA

Conjugate

Unconjugated

Cat No : 21269-1-AP

Print datasheet

Synonyms

CC1, DRAGOU14, FIP200, KIAA0203, RB1 inducible coiled coil 1, RB1CC1, RBICC

验证数据展示

  • WB analysis of HEK-293 using 21269-1-AP

    WB analysis of HEK-293 using 21269-1-AP

    WB result of RB1CC1 antibody (21269-1-AP, 1:1000) with si-Control and si-RB1CC1 transfected HEK293 cells.

  • WB analysis of HeLa using 21269-1-AP

    WB analysis of HeLa using 21269-1-AP

    HeLa cells were subjected to SDS PAGE followed by western blot with 21269-1-AP (RB1CC1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inHeLa cells, MCF-7 cells, HEK-293 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 21269-1-AP is RB1CC1 Fusion Protein expressed in E. coli.

Tested Applications WB,ELISA
Tested Reactivity human, mouse, rat
Immunogen RB1CC1 fusion protein Ag15739 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name RB1-inducible coiled-coil 1
Synonyms CC1, DRAGOU14, FIP200, KIAA0203, RB1 inducible coiled coil 1, RB1CC1, RBICC
Calculated Molecular Weight 1594 aa, 183 kDa
Observed Molecular Weight 200 kDa
GenBank Accession NumberBC017556
Gene Symbol RB1CC1
Gene ID (NCBI) 9821
RRIDAB_10733100
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8TDY2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

RB1CC1, also named as RBICC, is implicated in the regulation of RB1 expression and functions as a DNA-binding transcription factor. It is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Its expression is, thus, a prerequisite for myogenic differentiation. Involved in autophagy. RB1CC1 is required for autophagosome formation. It is probably involved in the tumorigenesis of breast cancer. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene. This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human RB1CC1.

实验方案

Product Specific Protocols
WB protocol for RB1CC1 antibody 21269-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols