验证数据展示
产品信息
15407-1-PBS targets RBM42 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | human, mouse, rat |
| Immunogen | RBM42 fusion protein Ag7667 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | RNA binding motif protein 42 |
| Synonyms | RNA-binding protein 42, RNA-binding motif protein 42, RBM 42 |
| Calculated Molecular Weight | 50 kDa |
| Observed Molecular Weight | 65-70 kDa |
| GenBank Accession Number | BC004204 |
| Gene Symbol | RBM42 |
| Gene ID (NCBI) | 79171 |
| RRID | AB_2176113 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BTD8 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
RBM42, also known as RNA-binding motif protein 42, is a member of the RNA-binding protein family that plays critical roles in post-transcriptional regulation of gene expression. Emerging studies highlight RBM42's involvement in pre-mRNA splicing through its association with the spliceosome complex, where it contributes to the precise removal of introns and assembly of mature mRNA. Beyond splicing, RBM42 has been implicated in cellular stress responses, cell cycle regulation, and apoptosis. Dysregulation of RBM42 is linked to developmental disorders and cancers; for instance, mutations in RBM42 are associated with neurodevelopmental abnormalities, while its overexpression or loss correlates with tumor progression in certain malignancies.
