验证数据展示
产品信息
84016-4-PBS targets REPS2 in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | REPS2 fusion protein Ag33764 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | RALBP1 associated Eps domain containing 2 |
| 别名 | REPS 2, RalBP1-interacting protein 2, RalBP1-associated Eps domain-containing protein 2, RalBP1 interacting protein 2, 241136D3 |
| 计算分子量 | 72KD |
| GenBank蛋白编号 | NM_004726 |
| 基因名称 | REPS2 |
| Gene ID (NCBI) | 9185 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q8NFH8 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
REPS2 is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. There are 4 isoforms of the protein with two short (58 kDa) isoforms comprising 521 or 522 amino acid residues and two long (78 kDa) ones of 659 or 660 residues.