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  • Featured Product
  • KD/KO Validated

RERG Polyclonal antibody

RERG Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA and More (2)

Conjugate

Unconjugated

Cat no : 10687-1-AP

Print datasheet

Synonyms

RERC, RERG

验证数据展示

  • WB analysis of MCF-7 using 10687-1-AP

    WB analysis of MCF-7 using 10687-1-AP

    WB result of RERG antibody (10687-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-RERG transfected MCF-7 cells.

  • WB analysis using 10687-1-AP

    WB analysis using 10687-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 10687-1-AP (RERG antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inNIH/3T3 cells, MCF-7 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10687-1-AP targets RERG in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF, IHC
Tested Reactivity human, mouse
Cited Reactivityhuman
Immunogen RERG fusion protein Ag1041 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name RAS-like, estrogen-regulated, growth inhibitor
Synonyms RERC, RERG
Calculated Molecular Weight 23 kDa
Observed Molecular Weight 23-26 kDa
GenBank Accession NumberBC007997
Gene Symbol RERG
Gene ID (NCBI) 85004
RRIDAB_2253772
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96A58
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

RERG (Ras-related and estrogen-regulated growth inhibitor), a gene that encodes a small GTP binding and hydrolyzing protein (GTPase) of the Ras superfamily, is a novel gene that was first reported in breast cancer. RERG gene expression is stimulated by the estrogen receptor alpha (ERalpha), and RERG gene expression is absent in ER-negative breast cancer. RERG can bind and hydrolyze GTP as a GTP/GDP molecular switch, and RERG has been shown to possess growth inhibitory activity in breast cancer cells.

实验方案

Product Specific Protocols
WB protocol for RERG antibody 10687-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IF

Front Oncol

The NFAT3/RERG Complex in Luminal Breast Cancers Is Required to Inhibit Cell Invasion and May Be Correlated With an Absence of Axillary Lymph Nodes Colonization.

Authors - Lucie Coillard
  • KD Validated
View Article
humanIHC

Breast Cancer Res Treat

RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype.

Authors - Habashy Hany Onsy HO
View Article

Oncol Rep

ERK5‑regulated RERG expression promotes cancer progression in prostatic carcinoma.

Authors - Ying Xiong
View Article
humanWB,IHC

Oncotarget

MicroRNA-382-5p aggravates breast cancer progression by regulating the RERG/Ras/ERK signaling axis.

Authors - Jar-Yi Ho
View Article
humanIHC

Front Med (Lausanne)

Missing link between tissue specific expressing pattern of ERβ and the clinical manifestations in LGBLEL

Authors - Xujuan Zhang
View Article