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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis of human heart using 11904-1-AP (same clone as 11904-1-PBS)

    WB analysis of human heart using 11904-1-AP (same clone as 11904-1-PBS)

    human heart tissue were subjected to SDS PAGE followed by western blot with 11904-1-AP (RGR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11904-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse retina using 11904-1-AP (same clone as 11904-1-PBS)

    IHC staining of mouse retina using 11904-1-AP (same clone as 11904-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse retina tissue slide using 11904-1-AP (RGR antibody) at dilution of 1:1000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11904-1-PBS in a different storage buffer formulation.

  • IP experiment of PC-3 using 11904-1-AP (same clone as 11904-1-PBS)

    IP experiment of PC-3 using 11904-1-AP (same clone as 11904-1-PBS)

    IP result of anti-RGR (IP:11904-1-AP, 4ug; Detection:11904-1-AP 1:300) with PC-3 cells lysate 4000ug. This data was developed using the same antibody clone with 11904-1-PBS in a different storage buffer formulation.

RGR Polyclonal antibody, PBS Only

RGR Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 11904-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

11904-1-PBS targets RGR in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 RGR fusion protein Ag2552 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 retinal G protein coupled receptor
别名
计算分子量 32 kDa
观测分子量 32 kDa, 26 kDa
GenBank蛋白编号BC008094
基因名称 RGR
Gene ID (NCBI) 5995
RRIDAB_2179498
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP47804
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

RGR is a G protein-coupled receptor preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. RGR acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The gene of PGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.