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RIPK1-IN-9

RIPK1-IN-9是是一种强效且具有选择性的 RIPK1抑制剂，是一种二氢萘酮化合物。RIPK1-IN-9对 U937细胞和 L929细胞具有抑制作用，IC50分别为2 nM 和1.3 nM。

CAS号

2682889-57-0

分子式

C26H25FN6O2

主要靶点

RIP kinase

仅限科研使用

Cat No : CM14083

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Synonyms

验证数据展示

  • CAS No.: 2682889-57-0

    RIPK1-IN-9
    CAS#: 2682889-57-0

产品信息

RIPK1-IN-9 is a potent and selective inhibitor of RIPK1, a dihydronaphthone compound, which inhibits U937 and L929 cells with an IC50 of 2 nM and 1.3 nM, respectively.

CAS号 2682889-57-0
分子式 C26H25FN6O2
主要靶点 RIP kinase
主要通路 NF-κB信号通路|凋亡
分子量 472.51
纯度 98.75%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件
别名

靶点活性

L929:1.3 nM|U937:2 nM

溶解度

DMSO:4.73 mg/mL (10 mM)

参考文献

1.Fusheng Zhou, et al. Dihydronaphthyridone compounds, their preparation and pharmaceutical uses. WO2021160109A1.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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=
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C1   V1   C2   V2