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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 68787-3-Ig (same clone as 68787-3-PBS)

    WB analysis using 68787-3-Ig (same clone as 68787-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68787-3-Ig (RNASEH1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68787-3-PBS in a different storage buffer formulation.

  • WB analysis using 68787-3-Ig (same clone as 68787-3-PBS)

    WB analysis using 68787-3-Ig (same clone as 68787-3-PBS)

    4T1 cells were subjected to SDS PAGE followed by western blot with 68787-3-Ig (RNASEH1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68787-3-PBS in a different storage buffer formulation.

RNASEH1 Monoclonal antibody, PBS Only

RNASEH1 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68787-3-PBS

产品说明书

CloneNo. 2C8D3

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

RNH1, RNASEH 1, RNase H1, EC:3.1.26.4, 2C8D3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68787-3-PBS targets RNASEH1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 RNASEH1 fusion protein Ag33948 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 ribonuclease H1
别名 RNH1, RNASEH 1, RNase H1, EC:3.1.26.4, 2C8D3
计算分子量 32 kDa
观测分子量 32 kDa
GenBank蛋白编号BC002973
基因名称 RNASEH1
Gene ID (NCBI) 246243
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDO60930
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Ribonucleases H are enzymes that cleave the RNA of RNA/DNA hybrids that form during replication and repair and which could lead to DNA instability if they were not processed. Eukaryotic RNases H are larger and more complex than their prokaryotic counterparts [PMID:12667461]. Eukaryotic RNase H1 has acquired a Hybrid Binding Domain that confers processivity and affinity for the substrate. Because of its essential role and its similarities in structure and enzymatic mechanism to the RNase H of HIV reverse transcriptase, RNASEH1 has been implicated in mitochondrial DNA replication during mouse development [PMID:19228196].