• Featured Product
  • KD/KO Validated

RND3 Polyclonal antibody

RND3 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

ELISA and More (3)

Conjugate

Unconjugated

Cat no : 12534-1-AP

Print datasheet

Synonyms

ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3



产品信息

12534-1-AP targets RND3 in WB, IP, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA Application Description
Cited ApplicationsWB, IP, IF
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, rat
Immunogen RND3 fusion protein Ag3235 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name Rho family GTPase 3
Synonyms ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3
Calculated Molecular Weight 244 aa, 27 kDa
GenBank Accession NumberBC012513
Gene Symbol RND3
Gene ID (NCBI) 390
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP61587
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.

发表文章

SpeciesApplicationTitle
humanWB,IP

Cancer Res

Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling.

Authors - Zehua Zhu
humanWB

J Mol Cell Biol

Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.

Authors - Zhou Yizhuo Y
RATWB,IF

J Am Heart Assoc

Rnd3 as a Novel Target to Ameliorate Microvascular Leakage.

Authors - Jerome W Breslin
  • KD Validated
ratWB

Life Sci

Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation.

Authors - Cui Zhai
humanWB

Mol Cell Biochem

MicroRNA-200b regulates cyclin D1 expression and promotes S-phase entry by targeting RND3 in HeLa cells.

Authors - Xia Wei W
  • KD Validated
humanWB

Cancer Lett

KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells

Authors - Meihua Shan