- Featured Product
- KD/KO Validated
RND3 Monoclonal antibody, PBS Only
RND3 Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, pig
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3H8F9
验证数据展示
产品信息
66228-1-PBS targets RND3 in WB, Indirect ELISA applications and shows reactivity with human, pig samples.
Tested Applications | WB, Indirect ELISA Application Description |
Tested Reactivity | human, pig |
Immunogen | RND3 fusion protein Ag18839 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Full Name | Rho family GTPase 3 |
Synonyms | ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3 |
Calculated Molecular Weight | 244 aa, 27 kDa |
Observed Molecular Weight | 29 kDa |
GenBank Accession Number | BC012513 |
Gene Symbol | RND3 |
Gene ID (NCBI) | 390 |
RRID | AB_2881619 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P61587 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.