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  • Featured Product
  • KD/KO Validated

RND3 Monoclonal antibody, PBS Only

RND3 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

3H8F9

Cat no : 66228-1-PBS

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Synonyms

ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3

验证数据展示

  • WB analysis of fetal human brain using 66228-1-Ig (same clone as 66228-1-PBS)

    WB analysis of fetal human brain using 66228-1-Ig (same clone as 66228-1-PBS)

    fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66228-1-Ig (RND3 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66228-1-PBS in a different storage buffer formulation.

产品信息

66228-1-PBS targets RND3 in WB, Indirect ELISA applications and shows reactivity with human, pig samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, pig
Immunogen RND3 fusion protein Ag18839 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name Rho family GTPase 3
Synonyms ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3
Calculated Molecular Weight 244 aa, 27 kDa
Observed Molecular Weight 29 kDa
GenBank Accession NumberBC012513
Gene Symbol RND3
Gene ID (NCBI) 390
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP61587
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.