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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • IHC staining of human liver using 26084-1-AP (same clone as 26084-1-PBS)

    IHC staining of human liver using 26084-1-AP (same clone as 26084-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 26084-1-AP (RNF217 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26084-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 26084-1-AP (same clone as 26084-1-PBS)

    IF Staining of HepG2 using 26084-1-AP (same clone as 26084-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using RNF217 antibody (26084-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26084-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 26084-1-AP (same clone as 26084-1-PBS)

    IHC staining of human liver using 26084-1-AP (same clone as 26084-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 26084-1-AP (RNF217 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26084-1-PBS in a different storage buffer formulation.

RNF217 Polyclonal antibody, PBS Only

RNF217 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 26084-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

26084-1-PBS targets RNF217 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 RNF217 fusion protein Ag22022 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ring finger protein 217
别名
计算分子量 275 aa, 32 kDa
观测分子量 59, 32 kDa
GenBank蛋白编号BC026087
基因名称 RNF217
Gene ID (NCBI) 154214
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8TC41
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

E3 ubiquitin-protein ligase RNF217, also known as IBR domain-containing protein 1 (IBRDC1), as a transmembrane (TM) domain-containing RBR-type E3 ubiquitin-protein ligase, belongs to a highly conserved member of the RING finger family. RNF217 mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis(Uniprot, PMID: 33895792).