RORC Polyclonal antibody

RORC Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (2)

Applications

WB, ELISA and More (3)

Conjugate

Unconjugated

Cat no : 13205-1-AP

Print datasheet

Synonyms

NR1F3, Nuclear receptor ROR gamma, Nuclear receptor RZR gamma, Nuclear receptor RZR-gamma, RAR related orphan receptor C, ROR gamma T, RORC, RORG, RORyT, RORγt, RZR GAMMA, RZRG, TOR



经过测试的应用

Positive WB detected inHEK-293 cells, Jurkat cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13205-1-AP targets RORC in WB, IF, IHC, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB, IF, IHC, ChIP
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, chicken, pig
Immunogen RORC fusion protein Ag3961 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name RAR-related orphan receptor C
Synonyms NR1F3, Nuclear receptor ROR gamma, Nuclear receptor RZR gamma, Nuclear receptor RZR-gamma, RAR related orphan receptor C, ROR gamma T, RORC, RORG, RORyT, RORγt, RZR GAMMA, RZRG, TOR
Calculated Molecular Weight 518 aa, 58 kDa
Observed Molecular Weight 58 kDa
GenBank Accession NumberBC031554
Gene Symbol RORC
Gene ID (NCBI) 6097
RRIDAB_2180306
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP51449
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The Nuclear receptors retinoic acid receptor-related orphan receptor gamma (RORγ or RORc, also known as NR1F3) was the third and most recent ROR group member to be discovered, following the prior disclosures of RORα (RORa or NR1F1) and RORβ (RORb or NR1F2) (PMID:24502334). Studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.RORC has 2 isoforms with the MW of 56 kDa and 58 kDa.

实验方案

Product Specific Protocols
WB protocol for RORC antibody 13205-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,ChIP

Oncogene

Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc

Authors - Ying-Nan Wang
ratIF

Headache

Aryl hydrocarbon receptors improve migraine-like pain behaviors in rats through the regulation of regulatory T cell/T-helper 17 cell-related homeostasis

Authors - Liu Yang
humanIHC

Front Oncol

Analysis of the potential association between ferroptosis and immune in hepatocellular carcinoma and their relationship with prognosis

Authors - Kai Wen
ratWB

Biomed Pharmacother

Yu Gan Long reduces rat liver fibrosis by blocking TGF-β1/Smad pathway and modulating the immunity.

Authors - Yu Xia
ratWB

Phytomedicine

Extracts of Poria cocos improve functional dyspepsia via regulating brain-gut peptides, immunity and repairing of gastrointestinal mucosa

Authors - Yijun Tu
mouseWB

Food Funct

Folic acid intervention changes liver Foxp3 methylation and ameliorates the damage caused by Th17/Treg imbalance after long-term alcohol exposure.

Authors - Huichao Zhao